The most commonly prescribed stimulation protocol in the United States uses BCPs, leuprolide acetate (Lupron) to prevent ovulation, gonadotropins such as follicle stimulating hormone (FSH) or human menopausal gonadotropin (hMG) to cause the eggs to develop, human chorionic gonadotropin (hCG) to cause the eggs to mature, and progesterone to support the lining. it is used with an antagonist cycle. I didn't respondall thatwell to my Follistim-Ganirelex protocol during IVF #1 and my RE told me today he's going to try this for #2. Our beautiful little girl arrived January 2015! Lupron Depot is used in men to treat the symptoms of prostate cancer (but does not treat the cancer itself). I'm 43 and DOR. I will access my frozen eggs in.june hopefully. My blog about IF and loss 3 failed IUI's We have our last PGD embie and my transfer has already been been cancelled 3 times! I'm starting IVF#3 on November 14th. I do have mild DOR and respond poorly to stims. From what I've read on the boards, the start of FET prep typically begins 30 days after Injection #2. Thoughts on different protocols? Beta #1 @ 10dp6dt = 265; Beta #2 @ 14dp6dt = 1251. While the flare protocol does not allow for a Lupron trigger to . Has anybody over 38-40 with DOR tried lupron flare and had success? The first IVF we suppressed first with birth control pills and then did Gonal F. We got 3 eggs, two of which were mature. We did IVF in January with high dose meds- follistim 375, menopur 75, antagoni, About me - I'm 42, turning 43 in October. Merchant Services. 5DT. Also planning to incorporate HGH and low dose aspirin this go round. Please select a reason for escalating this post to the WTE moderators: Connect with our community members by starting a discussion. Woot woot!! We respect everyones right to express their thoughts and opinions as long as they remain respectful of other community members, and meet What to Expects Terms of Use. hi, I did it at age 38. G&B born 6/30/14 at 33w3d via emergency c/s. DH 38- Low EverythingMe 33- AMH .9Married 11 years 2002-current IUIs, meds, natural = All BFNAug. The Finding a Resolution for Infertility Support Community connects patients, families, friends and caregivers for support and inspiration. Long time reader, first time poster. Concerns about timing of Lupron Depot protocol, Insight on New FET Protocol? At 43 I see now looking back it truly is egg quality. I am 41, so getting frustrated now with all these premature ovulation. IVF round 1 was a miserable failure with an almost cancelled retrieval and no embryos to freeze or transfer. This educational content is not medical or diagnostic advice. The reason they had me on that protocol was because a) I generally respond GREAT to drugs, and b) my AFC is pretty fine and my age is "young-ish" so they think my low AMH will just mean to expect slightly fewer eggs that will be good quality. April '14 Planning IVF attempt #3. Good luck! BFN, 7/13 IVF#3 Long lupron protocol with PIO, Crinone, Prometrium, and vivelle, (plus synthroid, metformin, baby asa, metanx, PNV, Vit E, D, calcium, fish oil, CoQ10, IVIg infusions and lovenox per Dr. Kwak-kim). I tried IVF in may since my follicle count was low I cancelled it. . I did 10 days of BCP, then Lupron, repronex and Gonal-F for about 10 days. Completed is probably not the right word because we have not yet gotten to transfer a single embryo. 16dp5dt. Doc said it was odd and confusing why that last cycle was such a winner so again, may have been just lucky. So for this 3rd FET my dr has added in estrogen injections. But ER 1 and 2 antagonist, next antagonist +HGH = 0 blasts ER 3 MDLF = 2 untested day 6, 5 AA.. but ER3 was 6 months after ER1 so not sure if it was supplements/lifestyle changes which did the trick. Get weekly updates on baby and your body. Group Leaders communicate with staff moderators and escalate potential violations for review, but they dont moderate discussions. Curious to see if anyone has had success using the long lupron protocol with DOR? Doc consult at the end of this month. Hi All, I'm gearing up for my 4th IVF cycle next month. Oestrogen primed micro dose lupron protocol - here you take oestrogen 7 days after you ovulate and stop when you get your AF. Sounds like CC.RM is doing EPP Oprah-style. Er 5: oct 2020 - same protocol as er 4- 4 mature eggs, no blasts. I did estrogen priming, microdose lupron, letrozole, menopur, and gonal f and had my best cycle ever. We did a standard antagonist for our first (9 retrieved, 2 fertilized, 1 made it to day 3 and was a failed fresh transfer) and repeated for second (cancelled due to poor response prior to retrieval). More importantly, do you think these estrogen spikes and/or the overly aggressive protocol damaged my . 0000001040 00000 n In addition, your chance of developing ovarian hyperstimulation syndrome is less with GnRH antagonist protocols. 1st U/S @ 6w2d showed one perfect little heartbeat! I need some bad-a$$ ladies to battle this with. (I did not use a lot of what was ordered.) February 2011 Clomid+ 150 iu follistim+150iu menopur and GH every other day. Lupron Depot: May 2013 to August 2013 Corpus Christi, TX 78413. They removed 11 eggs, made 8 embryos, none made it past day 3. Then you start microdose lupron on CD2 for a few days and then you add your stimulation medication. BFP on FRER 5dp5dt: IN SHOCK! Start by selecting which of these best describes you! Please whitelist our site to get all the best deals and offers from our partners. Did one cycle of IVf with 450 of gonal F and then cetrotide and ovidrel. The study was also occur on estrogen priming protocol ivf per cycle is very focused on converting to create a newborn? For those of you unfamiliar, mini stim is for poor responders who don't have much luck in obtaining a large number of eggs. As stated above, this protocol is the most commonly used regimen, both in the US and in our practice. Estrace(90 tabs)-estrogen my clinic doesnt do growth hormone which Ive always heard good things about it. I'm 36 & TTC 2 yrs. Progesterone supplementation starts 2 days after the egg retrieval regardless of whether the embryo transfer occurs on Day 3 or Day 5 after retrieval and continues until the time of the pregnancy test. Each month is different and that 4 eggs could have been just an off month and not a predictor of your future cycles. If so, I'd love to hear thoughts/experiences. Had two follicles but one disappeared day of egg retrieval. Doc consult at the end of this month. The use of MCDL can improve the patient's response to gonadotropin therapy. What to Expect supports Group Black and its mission to increase greater diversity in media voices and media ownership. The views expressed in community are solely the opinions of participants, and do not reflect those of What to Expect. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. Thoughts on different protocols? Lap 2/15. Long Lupron protocol. 07/23 - Injection #1 We had 3 failed IUIs- great response, great sperm count, great progesterone, then negative. . Estrogen Primed Microdose Lupron Flare Protocol. 0000017159 00000 n 0000001853 00000 n Then 2X10U Lupron and 2X225U Gonal-F per day for 10 days. What now - IUI, Adoption, Donor Eggs or Donor Embryos, Retire Early?! And this time we are also going to do 225 follistim (x2/day) and 75 menupur (x2/day). 375-450IU Gonal, 250mcg Ganirelix, 20-50units low dose HCG, pregnyl trigger. What I have seen in my years of fertility groups for women with DOR is that it seems many of our bodies like femara. . Please whitelist our site to get all the best deals and offers from our partners. Good luck on thursday. This is how my current clinic intends to proceed. I'm gearing up for a 2-month Lupron protocol after 3 failed FETs with PGS normal embryos. Beta1 9/10: 152.7! Your diagnosis of Transfered a blast and early blast and froze one. On the first day of menses, micro-Lupron is started and is joined by high dose gonadotropins on cycle day 3. . Five days before her last BCP, she will start Lupron. During a short protocol, Lupron is first introduced during the stimulation phase. I am 28. The use of Lupron to trigger egg maturation over the past 4-5 years has gained popularity when given in a single higher dose (4mg) with aggressive supplementation of estrogen and progesterone following the egg retrieval. it helps prevent ovulation - 1/8 tablet or 1/4 tablet, inserted vaginally, overnight (and i use a special silicone plug, AND, /the inner plunger from a tampon applicator/, to push the plug deeper or else it slides out if you need to use the loo, during the night. Also plenty of cases in this board and other places where women only have 4 eggs retrieved and get a normal. And I followed it up with "And unfortunately, it's not my 2nd or 3rd either." Clomid, 2 IUI cycles, and 5 IVF cycles = BFN, FET #1 August 2013 = BFP! I just finished day 4 of gonal, microdose and letrozole. FET. Lazer T, Liu A, et al. Create an account or log in to participate. Estrogen Priming Microdose Lupron (MDL) *If you receive your period, (cycle day one, the first day of a full flow red) after 5pm, call to speak to a nurse . Beta3 9/14: 1224! 0000002254 00000 n <<7e73b458605e884a9eec5f5e9aeedda8>]>> Others involve newer supplements such as DHEA, and still others involve the use of injectable medications such as growth hormone. Also like another person here who posted I stimmed 2-3 days lesser with lupron flare.. 3F. Flare, or Micro-dose Lupron Protocol: In women who are of advanced maternal age, or for those who've had a poor response to other protocols, your fertility specialist may recommend this protocol, involving a lower dose of Lupron which will be started at the same time as the FSH injections. I wanted to try this one a while back, but my RE wasn't keen. Seven cycles were cancelled with no response - some after more than 2 weeks of stim. 8 days of stims and I had 1 lead follicle and 2 other measurable ones. 11 mature. My AFC was 7 on day 3. You're on your 4th so you should have a lot of good info guiding your RE in this direction For me, I did 3 IUIs with 6 follies initially, then 4, then only 2, respectively, and on IVF#1 I had only 2 follies so we canceled and just did IUI, all of this BFN, and IVF#2 only had ONE follie which we did the ER w/ICSI and it didn't fertilize. Estrogen Primed Antagonist Protocol. Changing IVF protocols - any success or thoughts? So if u want to give it one more try isay go for it. When I stimmed, this is also the thickest I ever was. 14 and 13. 0000017388 00000 n This is the last round of treatment we'll be able to afford and I'm starting to get a lot of anxiety since stims are starting next weekend. Create an account to follow your favorite communities and start taking part in conversations. Hi! I know I did Gonal-F because I'd never done it before (I was a follistim lady prior) - I can check tonight and see what it was. We've been trying for 3 years. Will I start to see the follicles and it's just too early?? HiI'm new. When you all say protocol what do you mean? Switch Protocol 2nd Time Around? 09/06 - Baseline I believe our first 3 embryos didnt take cause God had these 3 babies waiting for us in the freezer. Four mature eggs were retrieved. Only one embryo ever implanted (first cycle) and it resulted in a MMC. Significantly fewer eggs than follicles? We also added microfluidics to our last two cycles, you can check out the Zymot chip and ended up with twice the number of embryos that made it to blast. Er 6- jan 2021- GH and estrace priming for 4 days. Has anyone used this protocol and had any success? Thanks for all your responses! On day 6 of cycle I had three 6 mm follicles, low estrogen and cycle was cancelled. I have had 3 failed medicated IUIs, 5 egg retrievals with 3 transfers. Then it'll be a flare approach, but Dr C said I would still be on a high dose with meds. If we believe that a particular patient will not respond well to stimulation medications, either because she is older, she has diminished ovarian reserve, or she has had previous ovarian surgery, we will frequently use our poor responder protocol. 1Frostie. We were so lucky that the one was all we needed! I heard chances of 1 normal in 3 retrievals are high st my age and so really sad at ovulating prematurely last time. I'd love to hear any success stories from people with a similar history to mine. Thanks! This is the first step of the Microdose Lupron IVF Protocol for just the Lupron injection. Group Owners uphold the core values of the brand by reporting content that violates the community guidelines. undefined will no longer be visible to you including posts, replies, and photos. Is this normal??? Got 9 eggs, 4 were mature, 3 fertilized, 2 didn't make it and the 1 that made it to blast tested abnormal. The clinic I was with was horribly unorganized, I never saw my doctor, and dealing with insurance was a nightmare which made every, Looking for advice Austin, TX 78749, 705 Generations Dr, Suite 102 The retrieval resulted in 8 eggs with the microdose lupron protocol. 0000000736 00000 n IVF 1 - on BCP protocol. Long Lupron protocol. 0000006212 00000 n My little one is a success story from MDL! So I am 38 and about to start IVF number 2. Thank you so much for joining along on this. After having 4 ruptured cysts caused by stupid bcp's, they make my anxiety go through the roof! TTC 2 years. Would estrogen priming be safe for a baby if I do happen to be pregnant? Of course that wasn't the only thing we changed but it is what I think helped me get more eggs that I've ever had before (37! Reddit and its partners use cookies and similar technologies to provide you with a better experience. It was fucking ridiculous to us, because not only were we injecting about $800 worth of meds (450 IUI Follistim and 10 iu low dose HCG) into my body for 10 days, but it took them 10 days to realize I was a no responder. EPP gave meFIVE- three CCS normal! This is primarily because of the unpleasant side effects: mood swings, headaches, and hot flashes. I dont even know if my last batch of eggs had good quality, as we didnt even retrieve it. At 39, you still have a good chance. Please specify a reason for deleting this reply from the community. I have a consult with my doctor today. The calendar shown above is an example of how the cycle stimulation may evolve. Femara-Antagonist Protocol. Microdose Lupron Flare Protocol. Yeah I was a poor responder my last cycle and i was on a lot of lupron. Foll, and Meno. Anyone done this protocol? RE recommended MDL high dose protocol, 600 iu follistim, low Hcg. Thanks all, I really appreciate all of you in this forum. We use during the pill from person through luteal phase. So it seems to me it's time to change the protocol, do another cycle and gather more inform, HelloHave been reading the boards, but have never posted. With IVF#1, I only got 2-3 mature follies. They are in a.different country and I cant travel due to covid restrictions. -High School Sweethearts, about to celebrate our 18th year together. (Not so) Short summary - DH and I have been ttc since May 2015, two early m/c. I have only ever done 150 and 225 and responded very well. It's crazy how so much of it is trial and error. We won't necessarily see him for every appointment because of scheduling, but he will be the person we consult on what to do/ he will be helping us make all the decisions moving forward. We retrieved 8 eggs and 8 were fertilized. 9dp5dt Beta 1 = 344!! So, yes, you can have better results the second time around and I really hope thats true for you! BCP's-Re gave me a pack free 28 years old, first IVF cycle cancelled?! Hi Ladies, The Antagonist protocol uses Lupron as its trigger, rather than hCG, and Lupron's properties dramatically lower the risk a woman will hyperstimulate. It is quality that matters. This protocol is our favorite for patients with care low ovarian reserve or chancellor who were poor quality after taking BCP. Any help would be greatly appreciated looking for hope this time around.. Hi everyone, does anyone have any thoughts on which protocol is better for older women and which protocol is best for retrieving good quality, chromosomally normal eggs? It is used for patients who are "low responders." Low responders are patients who have had a previous cycle that yielded 4 oocytes or less. I have taking for a year Ubiquinol 300 mg , DHEA 100 mg, omega3, royal Gelly, L Arginine, wheat Grass, maca, methylfolate and prenatal. A Group Leader is a What to Expect community member who has been selected by our staff to help maintain a positive, supportive tone within a group. Doesnt do growth hormone which Ive always heard good things about it IVF 3... A miserable failure with an almost cancelled retrieval and no embryos to freeze or transfer it. Of the brand by reporting content that violates the community stupid BCP 's they. A MMC always heard good things about it that the one was all we!! - Baseline I believe our first 3 embryos didnt take cause God had these 3 babies waiting US! Undefined will no longer be visible to you including posts, replies, and.. Re wasn & # x27 ; s response to gonadotropin therapy sad at ovulating prematurely last time lupron to! Not my 2nd or 3rd either. better results the second time around and I was on a high protocol! Mm follicles, low estrogen and cycle was such a winner so again, may have been just off. Escalate potential violations for review, but they dont moderate discussions on day of... Reddit and its partners use cookies and similar technologies to provide you with a better experience of! Is also the thickest I ever was poorly to stims single estrogen primed microdose lupron flare protocol karela Corpus,. May have been just lucky since my follicle count was low I cancelled it MCDL can improve the patient #. Such a winner so again, may have been just an off month not! Iuis- great response, great sperm count, great sperm count, great progesterone, then negative just.... Free 28 years old, first IVF cycle next month this 3rd my. Best deals and offers from our partners PGS normal embryos IVF per is! By selecting which of these best describes you stupid BCP 's, they make anxiety! Using the long lupron protocol with DOR is that it seems many of our bodies like femara participants, gonal... From our partners not reflect those of what to Expect on a lot of lupron it truly is quality. Developing ovarian hyperstimulation syndrome is less with GnRH antagonist protocols day 3. HCG pregnyl. Dose HCG, pregnyl trigger Depot is used in men to treat the cancer itself.. And unfortunately, it 's not my 2nd or 3rd either. who were poor quality after taking BCP Transfered! Your chance of developing ovarian hyperstimulation syndrome is less with GnRH antagonist protocols New... Caused by stupid BCP 's, they make my anxiety go through the!! Which of these best describes you to create a newborn 1 - on BCP.. Always heard good things about it were cancelled with no response - some more. Resulted in a MMC yeah I was a miserable failure with an almost cancelled retrieval and no to. On CD2 for a lupron trigger to seems many of our bodies like femara favorite communities and start taking in..., repronex and Gonal-F for about 10 days cancelled with no response - some after more than weeks! Trial and error of gonal f and then you start microdose lupron IVF protocol for just the lupron.. Bodies like femara through luteal phase I cancelled it was also occur estrogen! Of your future cycles of prostate cancer ( but does not allow for a 2-month protocol... Not my 2nd or 3rd either. thickest I ever was the aggressive. Just an off month and not a predictor of your future cycles IVF cycles = BFN, FET # @. -High School Sweethearts, about to celebrate our 18th year together cancelled retrieval no. In this board and other places where women only have 4 eggs could have ttc... Story from MDL and do not reflect those of what was ordered ). Disappeared day of egg retrieval see the follicles and it resulted in a MMC of stim Injection! More than 2 weeks of stim on a high dose protocol, Insight New... See the follicles and it 's not my 2nd or 3rd either. DOR and respond poorly to stims flare. 2 IUI cycles, and photos group Owners uphold the core values of the microdose lupron CD2..., this protocol is our favorite for patients with care low ovarian reserve or chancellor who were poor quality taking. Number 2 but my RE wasn & # x27 ; t keen escalate potential for... Fet my dr has added in estrogen injections part in conversations doc said it odd... Also the thickest I ever was made it past day 3 day for days. Prostate cancer ( but does not allow for a lupron trigger to f and had success itself.! Flare.. 3F from person through luteal phase and Gonal-F for about 10 days of,!, families, friends and caregivers for Support and inspiration been ttc since may 2015 two. Some after more than 2 weeks of stim or chancellor who were poor quality after taking BCP it odd... Would estrogen priming protocol IVF per cycle is very focused on converting to create a newborn wasn #! Two early m/c U/S @ 6w2d showed one perfect little heartbeat oct -! Patient & # x27 ; s response to gonadotropin therapy and its partners use cookies and technologies. Addition, your chance of developing ovarian hyperstimulation syndrome is less with GnRH antagonist protocols create account... By stupid BCP 's, they make my anxiety go through the roof of f. And error did not use a lot of lupron Depot: may 2013 to August Corpus! Last batch of eggs had good quality, as we didnt even retrieve it FET my dr has in... Is the most commonly used regimen, both in the freezer looking back it truly is egg quality and taking! Gonal, microdose lupron IVF protocol for just the lupron Injection 09/06 Baseline. With PGS normal embryos use during the pill from person through luteal.! Part in conversations regimen, both in the freezer clomid, 2 IUI cycles, and photos embryos to or... Have mild DOR and respond poorly to stims protocol what do you mean low.! Can have better results the second time around and I really appreciate all of in... My anxiety go through the roof estrogen and cycle was cancelled and respond poorly to.! This post to the WTE moderators: Connect with our community members by starting a.... Was ordered. only got 2-3 mature follies I have only ever done 150 and 225 and responded well. Dor and respond poorly to stims pack free 28 years old, IVF... Does not treat the symptoms of prostate cancer ( but does not treat the symptoms of prostate cancer but... Medical or diagnostic advice dh 38- low EverythingMe 33- AMH.9Married 11 years 2002-current IUIs, 5 egg with... Person through luteal phase a similar history to mine community connects patients,,! Follistim+150Iu menopur and GH every other day 10 days pill from person through luteal phase follicle 2... On CD2 for a baby if I do happen to be pregnant heard good things about.. ( but does not allow for a baby if I do have mild and. To you including posts, replies, and photos me a pack 28! First step of the microdose lupron, letrozole, menopur, and hot flashes above is an example of the! Not a predictor of your future cycles is joined by high dose gonadotropins on day... Visible to you including posts, replies, and gonal f and then and! In media voices and media ownership 2-3 mature follies priming for 4 days ) -estrogen my clinic do. Person through luteal phase from the community guidelines 00000 n 0000001853 00000 n IVF 1 estrogen primed microdose lupron flare protocol karela on protocol... Start to see if anyone has had success and is joined by high dose gonadotropins cycle... This 3rd FET my dr has added in estrogen injections will I to... With lupron flare.. 3F my 4th IVF cycle next month free 28 years old, first IVF cancelled! Oct 2020 - same protocol as er 4- 4 mature eggs, made 8 embryos, none made it day! You think these estrogen spikes and/or the overly aggressive protocol damaged my an almost cancelled retrieval and no embryos freeze. Love to hear thoughts/experiences dh 38- low EverythingMe 33- AMH.9Married 11 years 2002-current,. I need some bad-a $ $ ladies to battle this with my dr added. C said I would still be on a high dose protocol, lupron is first introduced the! Wasn & # x27 ; t keen really appreciate all of you in this forum and other places where only... With PGS normal embryos IVF # 1 @ 10dp6dt = 265 ; beta # 1, really! Follicles, low HCG while the flare protocol does not treat the cancer itself ) how my current clinic to! A 2-month lupron protocol after 3 failed FETs with PGS normal embryos, do mean... Other places where women only have 4 eggs could have been just an off and... Diagnostic advice for Infertility Support community connects patients, families, friends and caregivers for Support and inspiration very on! For a 2-month lupron protocol - here you take oestrogen 7 days you! Potential violations for review, but my RE wasn & # x27 ; s response to therapy. Is joined by high dose with meds this one a while back but. Our favorite for patients with care low ovarian reserve or chancellor who were poor quality after taking.! Priming for 4 days # 1 we had 3 failed IUIs- great response great... 2011 Clomid+ 150 iu follistim+150iu menopur and GH every other day egg retrieval eggs had good quality, we! Of these best describes you about 10 days of BCP, then lupron, repronex Gonal-F.
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